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Evaluating the effects of local endometrial injury on success of pregnancy rate in patients candidate for in vitro fertilization.

Evaluating the effects of local endometrial injury on success of pregnancy rate in patients candidate for in vitro fertilization (IVF).

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140224016705N11
Enrollment
324
Registered
2021-11-05
Start date
2021-07-23
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: Includes infertile women with at least one failed IVF history and re-candidate for IVF referred to the Reproductive Clinic of Mahdieh Hospital in Tehran, whose endo

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: History of infertility with a history of unsuccessful IVF candidate for in vitro fertilization Existence of inappropriate endometrial thickness based on ultrasound Age 40 years or less Do not use OCP or GnRH for FET in the previous cycle Appropriate quality of embryos for transfer

Exclusion criteria

Exclusion criteria: Vaginal or cervical active infection Endometrial Hyperplasia Existence of endometritis Presence of known intrauterine pathologies on ultrasound or hysteroscopy such as fibroids or myomas Asherman syndrome Uterine anomaly

Design outcomes

Primary

MeasureTime frame
Existence of clinical pregnancy (formation of pregnancy sac and fetal heart) in IVF patient under the intervention of endometrial abrasion with papillae. Timepoint: 5 weeks after the transfer, transvaginal ultrasound will examine the presence of clinical pregnancy (formation of pregnancy sac and fetal heart). Method of measurement: transvaginal ultrasound.;ß-hCG positivity (greater than 10 mIU / mL). Timepoint: ?-hCG titer was checked 2 weeks after embryo transfer. Method of measurement: Using a laboratory-approved ß-hCG test.;The effect of endometrial abrasion on endometrial condition. Timepoint: On day 8-10 of the cycle, an ultrasound will be performed again and the condition of the endometrium will be examined. Method of measurement: transvaginal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactzahra heidar

Shahid Beheshti University of Medical Sciences

dr_zheidar@yahoo.com+98 21 5506 2628

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026