unilateral ischemic stroke. Cerebral infarction, unspecified
Conditions
Interventions
Intervention 1: Intervention group: In this group, transcranial Direct Current Stimulation (tDCs) along with Task-Oriented Training are given for three weeks, 5 sessions per week, and each session for
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Having a first unilateral ischemic stroke as confirmed by the MRI or CT-Scan At least 6 months have passed since the unilateral stroke Having the ability to walk for at least 10 meter (with or without cane) Having motor dysfunction in upper limb with a degree of recovery equal or more than 4 according to the recovery stages of Brunnstrom Having a score equal or above 26 in the "Montreal Cognitive Assessment"
Exclusion criteria
Exclusion criteria: Having moderate to severe depression (a score of 19 or higher on the "Beck depression scale") Received Botox in the previous 6 months (to enter the study, patients must not have received Botox in the past six months) Having a contracture in the wrist and fingers of the affected side Having other neurological disorders such as Parkinson, Multiple Sclerosis and etc. Having a thalamic stroke or central pain syndrome (Dejerine Roussy Syndrome) Pain in the affected shoulder (having a score of less than 12 based on the Pain Assessment section of the "Fugle-Meyer assessment" of the upper extremity) Using drugs that affect the central nervous system Having pace maker or other stimulation or ferromagnetic implants Having a history of Seizures in the last two years and taking anticonvulsant drugs during one month before the enrollment in the current study Pregnancy unwillingness and lack of cooperation to continue the treatment Having serious and persistent skin complications or sleep and concentration disorders due to stimulation with tDCs Not completing the treatment period or occurrence of an accident that affects the motor function or brain activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalography parameters include "Absolute power" and "Relative power" and "Average frequency" within each frequency subband (delta, theta, alpha, beta and gamma). Timepoint: before treatment, after treatment (15th session), and 3 months later. Method of measurement: EEG recording. | — |
Secondary
| Measure | Time frame |
|---|---|
| Upper limb motor function ability by the "Wolf Motor Function Test". Timepoint: before treatment, after treatment (15th session), and 3 months later. Method of measurement: "Wolf Motor Function Test".;Upper limb motor function by the upper extremity part of the "Fugl-Meyer Assessment". Timepoint: before treatment, after treatment (15th session), and 3 months later. Method of measurement: Upper Extremity part of the "Fugl-Meyer Assessment".;Patient's ability to handle objects of different sizes, weights and shapes. Timepoint: before treatment, after treatment (15th session), and 3 months later. Method of measurement: "Action Research Arm Test". | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShohreh Noorizadeh Dehkordi
Iran University of Medical Sciences
Outcome results
None listed