Probiotic yogurt consumption on weight loss

Comparison of daily consumption of probiotic versus low fat conventional yoghurt on weight loss in healthy obese women on an energy restricted diet (Novin Diet Protocol): a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201402177754N8

Enrollment

Registered

2014-03-11

Start date

2014-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Obesity due to excess calories

Interventions

Intervention 1: intervention group: consumption of 400 gram low-fat-probiotic yogurt per day. Intervention 2: placebo group: consumption of 400 gram low fat conventional yogurt per day.

Behavior

intervention group: consumption of 400 gram low-fat-probiotic yogurt per day.

placebo group: consumption of 400 gram low fat conventional yogurt per day.

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Willingness to enrollment to the study;Waist circumference > 88 cm;Non smoking; No-menopause;BMI: 25-45 kg/m2;Good general health;Normal lipid level (healthy obese);No- diabetes;Able to give informed consent and report side effects; Exclusion criteria:Antibiotic treatment;Drugs that control glucose or lipid profiles; Pregnancy or have given birth in the past year or planning pregnancy in the next 6 months;Lactation;Menopause women;Cancer or chemo/radio therapy;Chronic disease;Competitive athletes;Consumption of probiotic products;History of alcohol use;Abnormal thyroid hormone level;PCOD women;Intake of medications that could affect body weight and/or energy expenditure;Family history of T2DM in first degree relatives Allergy to probiotic or dairy products;Anemia;Recent history of large weight fluctuations;Immune compromised conditions; Current use of antihypertensive medications; depression; Prediabetes; Smoking; CVD; Active colitis; Solid organ transplant; Fatty liver

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Body weight. Timepoint: 0 and 12 weeks. Method of measurement: balance.	—

Secondary

Measure	Time frame
Waist circumference. Timepoint: 0 and 12 weeks. Method of measurement: meter.;Fasting insulin level. Timepoint: 0 and 12 weeks. Method of measurement: ELISA kit.;Insulin resistance. Timepoint: 0 and 12 weeks. Method of measurement: HOMA-IR.;Hs-CRP. Timepoint: 0 and 12 weeks. Method of measurement: ELISA.;Lipid profiles. Timepoint: 0 and 12 weeks. Method of measurement: autoanalyzer.;Liver function tests. Timepoint: 0 and 12 weeks. Method of measurement: Autoanalyzer.	—

Measure

Time frame

Waist circumference. Timepoint: 0 and 12 weeks. Method of measurement: meter.;Fasting insulin level. Timepoint: 0 and 12 weeks. Method of measurement: ELISA kit.;Insulin resistance. Timepoint: 0 and 12 weeks. Method of measurement: HOMA-IR.;Hs-CRP. Timepoint: 0 and 12 weeks. Method of measurement: ELISA.;Lipid profiles. Timepoint: 0 and 12 weeks. Method of measurement: autoanalyzer.;Liver function tests. Timepoint: 0 and 12 weeks. Method of measurement: Autoanalyzer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Hamidreza Farshchi

Novin Diet Clinic

hrfarshchi@gmail.com+98 21 2226 3002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 14, 2026