preeclampsia. Gestational [pregnancy-induced] hypertension with significant proteinuria
Conditions
Interventions
Intervention 1: Control group: folic acid 0.5mg/day from the beginning of the pregnancy to the end. Intervention 2: Intervention group: folic acid 5mg/day from the beginning of the pregnancy to the en
Treatment - Drugs
Control group: folic acid 0.5mg/day from the beginning of the pregnancy to the end.
Intervention group: folic acid 5mg/day from the beginning of the pregnancy to the end.
Sponsors
?Drug Applied Research Center, Tabriz University of Medical Sciences and Health Services
Eligibility
Sex/Gender
Female
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Healthy mothers with a singleton pregnancy aged between 20-30 years old Exclusion criteria: Heart disease; chronic hypertension; Diabetes mellitus; collagen vascular diseases; chronic renal disease; preterm delivery for the other reasons except preeclampsia; taking medications other than calcium and ferrous sulfate and vitamin B6.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreasion in homocysteine level. Timepoint: first trimester and at delivery time. Method of measurement: serum sampeling.;Prevention of preeclampsia. Timepoint: after 20th week of pregnancy age. Method of measurement: controling of severe signs, body weight, blood pressure, edema, urine protein in every visit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Preterm labor. Timepoint: labor after 20-37. Method of measurement: clinical examination.;Prevention of IUGR. Timepoint: After 24 weeks every month. Method of measurement: sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactManizheh Sayyah-Melli
Tabriz University of Medical Sciences
Outcome results
None listed