The effects of adding intrathecal midazolam to bupivacaine in spinal anesthesia

The effects of adding intrathecal midazolam to bupivacaine in spinal anesthesia for pain reduction in lower limb orthopedic surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014021716612N1

Enrollment

Registered

2014-06-06

Start date

2014-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain. Other surgical procedures

Interventions

Intervention 1: for control group3 ml bupivacain 0.5 % with 0.4 ml saline. Intervention 2: for intervention group 3 ml bupivacain 0.5% with 0.4 ml midazolam (2 mg).

Prevention

for control group3 ml bupivacain 0.5 % with 0.4 ml saline

for intervention group 3 ml bupivacain 0.5% with 0.4 ml midazolam (2 mg)

Eligibility

Sex/Gender

All

Age

15 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for lower limb orthopedic surgery, aged 15 to 80 years Exclusion criteria: Patients with impaired consciousness, lack of patient cooperation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: per hour upto 6 hour after operation. Method of measurement: visual analoug scale.	—

Secondary

Measure	Time frame
Postoperative sedation. Timepoint: 6 hour after surgery. Method of measurement: Ramsy scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Khatereh Isazadehfar

Ardabil University of Medical Sciences

isazadehfar@yahoo.com kh.isazadehfar@arums.ac.ir+98 45 1223 6680

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026