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The Effect of Letrozole on Symptomatic Uterine Leiomyoma

The Effect of Letrozole on Symptomatic Uterine Leiomyoma in premenopausal women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201402161760N32
Enrollment
40
Registered
2014-07-05
Start date
2014-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic Uterine Leiomyoma. Leiomyoma of uterus

Interventions

Letrozole drug produced by the pharmaceutical company Soha the amount of 2.5mg / d is administered to patients for a period of twelve weeks..
Treatment - Drugs
Letrozole drug produced by the pharmaceutical company Soha the amount of 2.5mg / d is administered to patients for a period of twelve weeks.

Sponsors

Vice Chancellor for Research of Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 42 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Premenopausal women aged 42-18 years with a single Intramural leiomyoma size> 5 cm; Women with uterine myoma> 5cm with other myoma size 2cm; Women with uterine leiomyomas treated with estrogen or progesterone last month; Women with a history of major medical problems or previous medical or surgical treatment for leiomyomas; All women with leiomyoma sizes 2 to 5cm

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Leiomyoma tumors. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: Ultrasound.;Uterine volume. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: ?????????.

Secondary

MeasureTime frame
Serum gonadotropin. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: Laboratory.;Serum Estradiol. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: Laboratory.;Menstrual pattern. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: clinical.;Clinical symptoms associated with leiomyoma. Timepoint: On admission and on days 30 and 90 after treatment. Method of measurement: clinical.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Asieh Khodami

Hospital Ayatollah Rouhani

drhoseininejad@yahoo.com+98 11 1223 8284

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026