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Efficacy of embryo culture on freezed embryos and pregnancy outcome

Evaluation of efficacy of GM-CSF in embryo culture for freezed embryos in embryo development and pregnancy outcomes

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014021611430N4
Enrollment
80
Registered
2014-03-17
Start date
2014-03-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In vitro fertilization. In vitro fertilization

Interventions

In intervention group , embryos after thawing will cultured in medium with growth factor and in control group they will cultured in medium without growth factor. IN two groups will evaluate Blastocyst
Treatment - Other

Sponsors

Infertility and recurrent abortion treatment center of Avicenna
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 42 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1)Couples that undergoing treatment whit own gametes 2)women under 40 ears old 3)Women whit at least 4 good quality embryo after thawing(grade A) 4)Women that did not have more than 1 previous embryo transfer Exclusion criteria: 1)Cycles whit no PGD(Preimplantation genetic diagnosis) 2)Women whit no uterine anatomic disorder or hydrosalpinx

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Development of embryos to blastocysts. Timepoint: 5 days after intervention. Method of measurement: Microscopic evaluation of embryos.;Implantation rate. Timepoint: 5 weeks after intervention. Method of measurement: Vaginal ultrasonography.;Clinical pregnancy rate. Timepoint: 6 weeks after intervention. Method of measurement: Vaginal ultrasonography.

Secondary

MeasureTime frame
Quality of embryos. Timepoint: 5 days after intervention. Method of measurement: Microscopic evaluation of embryos.;Beta HCG level. Timepoint: 19 days after intervention. Method of measurement: Blood sample evaluation.;Evaluation of abortion under 12 weeks. Timepoint: 12 weeks after intervention. Method of measurement: History of patient.;Multiple pregnancy. Timepoint: 5 weeks after intervention. Method of measurement: Vaginal ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZafardoust Simin

Infertility and recurrent abortion of Avicenna

Sadeghi@avicenna.ac.ir s.zafardoost@avicenna.ac.ir+98 21 2264 4701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026