The effects of probiotic yoghurt on type 2 diabetes

Effects of probiotic yogurt consumption on some inflammatory biomarkers ( hs-CRP,IL-6,TNF-a),glacated hemoglobine,lipid profile and gi symptoms in patients with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014021516588N1

Enrollment

Registered

2014-03-04

Start date

2012-01-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: The subjects in the intervention group consume 300 g/d probiotic yogurt containing 106 colony of both Lactobacillus acidophilus and Bifidobacterium lactis bacteria. Intervention 2: Su

Treatment - Drugs

The subjects in the intervention group consume 300 g/d probiotic yogurt containing 106 colony of both Lactobacillus acidophilus and Bifidobacterium lactis bacteria

Subjects in the control group consume 300g/d conventional yogurt.

Eligibility

Sex/Gender

All

Age

35 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having type 2 diabetes, 35 to 55 years old, BMI =30, LDL level more than 100 mg/dl. Exclusion criteria: cardiovascular disease,renal dysfunction,chronic inflammatory diseases; inflammatory bowel disease, thyroid disorders and lactose intolerance, treatment with insulin and taking corticosteroids, NSAIDS, immunosuppressives, cholesterol lowering drugs, multivitamin-mineral , fiber and omega 3 supplements, smoking, pregnancy and lactation, having any weight loose or weight gain regimes, use of antibiotics

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemoglobin A1c. Timepoint: Before and after 8 weeks. Method of measurement: Chromatography.;Fasting Blood Sugar. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;Total Cholesterol. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;HDL-c. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;LDL-c. Timepoint: Before and after 8 weeks. Method of measurement: Friedewald Formula.;Hs-CRP. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;TNF-a. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;Interlukine-6. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;Gi symptoms. Timepoint: Before and after 8 weeks. Method of measurement: Gi symptoms questionarie.	—

Measure

Time frame

Hemoglobin A1c. Timepoint: Before and after 8 weeks. Method of measurement: Chromatography.;Fasting Blood Sugar. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;Total Cholesterol. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;Triglyceride. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;HDL-c. Timepoint: Before and after 8 weeks. Method of measurement: Spectrophotometry.;LDL-c. Timepoint: Before and after 8 weeks. Method of measurement: Friedewald Formula.;Hs-CRP. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;TNF-a. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;Interlukine-6. Timepoint: Before and after 8 weeks. Method of measurement: ELISA.;Gi symptoms. Timepoint: Before and after 8 weeks. Method of measurement: Gi symptoms questionarie.

—

Secondary

Measure	Time frame
Dietary Factors. Timepoint: Before and after 8 weeks. Method of measurement: 3-day 24h dietary recalls.;Hip circumference. Timepoint: Before and after 8 weeks. Method of measurement: Meter.;Body weight. Timepoint: Before and after 8 weeks. Method of measurement: Digital scale.;Waist circumference. Timepoint: Before and after 8 weeks. Method of measurement: Meter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Mohammadi

School of Paramedicine, Ahvaz Jondishapur University Of Medical Sciences

f.mohamadi2008@gmail.com+98 61 1373 8253

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026