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Effect of an orthodontic nano composite on bacterial plaque

Comparison of a modified orthodontic composite containing nano TiO2 particles and conventional orthodontic copmposites in reducing Streptococcus mutans of dental plaque in fixed orthodontic patients; a split-mouth randomized controlled clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140215016582N6
Enrollment
30
Registered
2021-10-19
Start date
2021-09-19
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

caries and demineralization. Dental caries on smooth surface limited to enamel

Interventions

Intervention 1: Intervention group: bonding brackets with composite containing TiO2 nanoparticles. the nanoparticles are 100% anatase phase and will be added with 0.01% concentrartion. Intervention 2:
3M brand.

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 25 Years

Inclusion criteria

Inclusion criteria: Patients ranged 12-25 years old The ability to observe the hygiene of a mouth They must have 1-4 repaired teeth A healthy and flawless immune system Non-use of antibacterial mouthwashes and antibiotics during treatment

Exclusion criteria

Exclusion criteria: Loss of tooth due to decay Presence of active decay or prosthetic treatment in the mouth Smoking Periodontal disease Under treatment with immunosuppressive drugs Diabetic patient pregnancy

Design outcomes

Secondary

MeasureTime frame
?Demineralization. Timepoint: Before intervention and 1 month after intervention. Method of measurement: ?Diagnodent laser.

Primary

MeasureTime frame
S.mutans count of dental plaque. Timepoint: Before intervention and one month after intervention. Method of measurement: Colony count.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactvahid mollabshi

Hamedan University of Medical Sciences

vahidmolabashi@yahoo.com0098 81 8216072

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 12, 2026