Pityriasis versicolor. Pityriasis versicolor
Conditions
Interventions
Intervention 1: Intervention: Application of Tacrolimus 0.03% ointment two times a day for 21 days. Intervention 2: Control: Application of Clotrimazole 1% cream two times a day for 21 days.
Treatment - Drugs
Intervention: Application of Tacrolimus 0.03% ointment two times a day for 21 days
Control: Application of Clotrimazole 1% cream two times a day for 21 days
Sponsors
Research Council of Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
10 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Clinical diagnosis of tinea versicolor; Confirmation of diagnosis by Wood's lamp examination (Yellow fluorescence) and Direct smear; Patients of 10 year old and over; Less than 15% of body surface area involvement Exclusion criteria: Pregnancy or Lactation; History of hypersensitivity to main or preservative ingredients of topical tacrolimus or clotrimazole; Serious skin or systemic diseases; History of consumption of topical or systemic antifungal medications in the recent 1 month before enrolling in study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wood's lamp fluorescence. Timepoint: 0, 3rd, and 5th week. Method of measurement: Wood's lamp radiation.;Scale and hyperpigmentation grade. Timepoint: 0, 3rd, and 5th week. Method of measurement: Physician global assessment.;Malassezia species positivity. Timepoint: o, 3rd and 5th weeks. Method of measurement: Direct KOH 10% smear. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pruritus. Timepoint: 0, 3rd, and 5th week. Method of measurement: Visual assessment scale.;Hypopigmentation. Timepoint: 0, 3rd, and 5th week. Method of measurement: Physician global assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Sadat Sadat
Shiraz University of Medical Sciences
Outcome results
None listed