Striae distensae. Striae atrophicae
Conditions
Interventions
Intervention 1: Intervention group: Nanofat grafting in the striae of one side of the body (one session at the beginning of study). Intervention 2: Control group: microneedling in striae of one side o
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: patients of 18 to 60 years of age bilateral striae distensae (alba and rubra) site on the abdomen, buttock, calves, thighs, and arms
Exclusion criteria
Exclusion criteria: pregnancy lactation body mass index less than or equal to 22 history of nickel hypersensitivity history of treatment for striae in the recent one year history of hypertrophic scar or keloid formation active infections on the study area severe underlying internal diseases history of hypercoagulation states Consumption of immunosuppressant drugs, systemic retinoids, corticosteroids, and anabolic steroids in the recent 2 months history of allergy to any ingredient of tumescent anesthetic solution history of abdominoplasty scar on the fat donor site history of Cushing syndrome history of polycystic ovary syndrome body dysmorphic disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical improvement of striae. Timepoint: The patients will be assessed in 3 monthly visits for microneedling, and 6 months after the first visit. Method of measurement: Global aesthetic improvement scale, measured as: Grade 0: Worsening of lesions; Grade 1: No change (< 25% improvement); Grade 2: Improved (25-50% improvement); Grade 3: Much improved (51-75% improvement); Grade 4: Very much improved (76-100% improvement). | — |
Secondary
| Measure | Time frame |
|---|---|
| Striae size reduction. Timepoint: 3 monthly visits for microneedling, and 6 months after the first visit. Method of measurement: Percentage of striae width reduction.;Striae color. Timepoint: At the beginning of treatment, 3 monthly visits for microneedling, and 6 months after the first visit. Method of measurement: Pigment index is measured by colorimetric device.;Dermoscopic features of striae. Timepoint: At the beginning of treatment, 3 monthly visits for microneedling, and 6 months after the first visit. Method of measurement: Dermatoscopic features like color, vascularity, width, and texture of striae.;Patient satisfaction. Timepoint: At the end of treatment. Method of measurement: ?A 5-point scale. 4: Extremely satisfied, 3:Very satisfied, 2: satisfied, 1: Slightly satisfied, 0: Not satisfied.;Pain during treatment. Timepoint: At the 3 sessions of monthly treatment. Method of measurement: Pain illustrated numerical rating scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhdeh Sepaskhah
Shiraz University of Medical Sciences
Outcome results
None listed