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Comparing the effectiveness of ophthalmic vitamin A ointment and moisture chamber to prevent ocular surface disorders in critically ill patients

Comparing the effectiveness of ophthalmic vitamin A ointment and moisture chamber to prevent ocular surface disorders in critically ill patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201402116318N3
Enrollment
15
Registered
2014-03-19
Start date
2014-02-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Surface disorders. Other keratitis

Interventions

Intervention 1: After standard eye care (washing the eye and the skin around the eye with five to 10 cc saline), one of the patient' eye were randomized receives a piece of thin layer of transparent p
Treatment - Drugs
After standard eye care (washing the eye and the skin around the eye with five to 10 cc saline), one of the patient' eye were randomized receives a piece of thin layer of transparent polyethylene to c
After standard eye care (washing the eyelids and the skin around the eye with five to 10 cc saline), one of the patient' eye were randomized, every 6 hour, about two centimeters the vitamin A ophthalm

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: over 18 years old; corneal health in the initial of examination; hospitalized in intensive care unit at least for three days; conscious degree less than 8 according to Glasgow Coma Scale; inexistence of face or eye trauma; inexistence of eye problems history. Exclusion criteria: Existence of chemosis, eye lid position grade difference in the initial of examination; Bell’s palsy or hemiplegia; also if patient is capable of blinking for three days; corneal disorder at any stage of the test, recorded and the patient excluded from study continuing.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ocular surface disorders. Timepoint: In 1th to 5th days. Method of measurement: The assessment tool of ocular surface disorders in this study is including Schirmer and Fluorescein tests. Schirmer test is done one time before the initiation and one time at the end of the study. To do the test Schirmer's graded paper will inserted in inferior fornix of lower eyelid at the junction of the middle third and outer third of the eyelid and the eyelid is closed and after five minutes, the height of the paper moist is measured in millimeters. Fluorescein test done daily till five days. Thus after corneal staining with fluorescein, existence of corneal damage assess by using pen light with blue light (cobalt) and 20 diopter lens and the test result is ranking according to Oxford grading scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Monir Nobahar

Semnan University of Medical Sciences

Nobahar43@sem-ums.ac.ir Nobahar43@yahoo.com+98 23 1335 4170

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026