Tympanoplasty. Perforation of tympanic membrane
Conditions
Interventions
Intervention 1: In intervention group Hyaluronic Acid applied inside and outside of middle ear. Intervention 2: In control group Gelfoam applied inside and outside of middle ear.
Treatment - Surgery
In intervention group Hyaluronic Acid applied inside and outside of middle ear.
In control group Gelfoam applied inside and outside of middle ear.
Sponsors
Vice Chancellor of Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients more than 18 years old; tympanic perforation =50 %. Exclusion criteria: Patients suffered from underlying diseases such as: asthma, diabetes, coagulation disorders, cardiovascular disease, basic metabolic disorder, immune system deficiency and chronic liver or renal disease; Smokers; Revision tympanoplasty; Patients with contra-lateral ear disease; Presence of cholesteatoma; Presence of tympanosclelerotic plaque in middle ear; Presence of granulation tissue in middle ear.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tympanic membrane graft success rate. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Hearing threshold. Timepoint: before operation, 6 months after operation. Method of measurement: pure tone audiometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSareh Roosta
Center for Development of Clinical Studies, Vice Chancellor of Research and Technology, Shiraz Unive
Outcome results
None listed