Schizophrenia. Schizophrenia
Conditions
Interventions
Intervention 1: in intervention group 50 mg topiramate added to their daily treatment in 12 week. Intervention 2: in intervention group100 mg topiramate added to their daily treatment in 12 week. Inte
Treatment - Drugs
in intervention group 50 mg topiramate added to their daily treatment in 12 week.
in intervention group100 mg topiramate added to their daily treatment in 12 week
in intervention group200 mg topiramate added to their daily treatment in 12 week
in control group placebo added to their daily treatment in 12 week.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria included: Schizophrenia according to DSM-IV-IR; aged between 18-60 years. Exclusion criteria included: Substance abuse in the past six months, a history of seizures, concomitant use of other drugs except benzodiazepines and beta-blockers .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: 0,1,2,4,6,8,12 weeks. Method of measurement: Balance.;Around the wrist. Timepoint: 0,4,8,12 weeks. Method of measurement: Meter.;Waist. Timepoint: 0,4,8,12 weeks. Method of measurement: meter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical tests (FBS,UREA, TG, SGOT,SGPT,Cholestrol). Timepoint: Baseline and end of plan. Method of measurement: in Laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammd Reza Fayyazi Bordbar
Mashhad University of Medical Sciences
Outcome results
None listed