QT Prolongation. Electrocardiogram [ECG][EKG]
Conditions
Interventions
In intervention group we use alfentanil 20-25 microgram/kg in induction and with rate of 0.5-2 microgram/kg/min in maintenance .In control group remifentanil is use with dose of 1-2 microgram/kg in i
Prevention
Sponsors
Vice Chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with physical status class I -II, based on the classification of the American Society of Anesthesiologists (ASA) and the age up to50 years undergoing septoplasty. Exclusion criteria: the use of any effective drug on QT interval in 14 days before surgery (TCA); beta antagonist, anti-arrhythmic, the calcium channel blocker) ; QTc more than 440 m/s; The existence of branches blocks, arrhythmia (preexitation syndrome) ; Structural heart disease.; electrolyte imbalance; hyper or hypothyroid patients 7. Extreme Obesity BMI 30 >; Diabetic neuropathy; Any non- sinus rhythm in EKG; A history of sensitivity to propofol, egg and soy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QT interval. Timepoint: Prioperative /Six times. Method of measurement: EKG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate Monitoring. Timepoint: Six Times Perioperative. Method of measurement: EKG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Toobaei
Shiraz University of Medical Sciences
Outcome results
None listed