Irritable bowel syndrome. Irritable bowel syndrome
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive two capsule of spirulina (containing 500 mg of spirulina platensis powder) daily after breakfast for 12 weeks. Intervention 2:
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Ages range of 18-50 years patients diagnosed with irritable bowel syndrome through ROME IV criteria by a gastroenterologist
Exclusion criteria
Exclusion criteria: Smoking Alcohol consumption Pregnancy or breastfeeding condition Taking antidepressants and anxiety medications. Taking antioxidant and omega-3 supplements in the last three months Kidney, liver, thyroid and parathyroid, heart disease, cancer and gastrointestinal diseases other than IBS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: At baseline and after 12 weeks. Method of measurement: Irritable bowel syndrome-quality of life- 34 (IBS-QOL-34)questionnaire.;Disease severity. Timepoint: At baseline and after 12 weeks. Method of measurement: Irritable bowel syndrome syndrome severity scale(IBS-SSS) questionnaire.;Serum zonulin level. Timepoint: At baseline and after 12 weeks. Method of measurement: Eliza kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total antioxidant capacity of serum. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method.;Malonaldehyde. Timepoint: At baseline and after 12 weeks. Method of measurement: Colorimetric method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad hassan entezari
Esfahan University of Medical Sciences
Outcome results
None listed