Nonalcoholic Fatty Liver Disease.. Nonalcoholic steatohepatitis (NASH)
Conditions
Interventions
Intervention 1: Intervention group will take 500 mg of sour tea tablets, for 8 weeks. Intervention 2: Control group will take placebo tablets with identical appearance containing starch for 8 weeks.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
23 Years to 55 Years
Inclusion criteria
Inclusion criteria: Patients with the nonalcoholic fatty liver disease confirmed with imaging techniques. Body Mass Index (BMI) of them is greater than 24.9 and lower than 40.
Exclusion criteria
Exclusion criteria: Alcohol consumption Pregnant and lactating women Any known forms of hepatic or metabolic disease except NAFLD, such as hereditary hemochromatosis, Wilson’s disease, cirosis, other metabolic disease history of gastric bypass or intestine surgery Taking hepatotoxic drugs such as calcium channel blocker, methotrexate, amiodarone, chloroquine and anti inflammatory drugs Using antioxidant supplements Hormone Therapy Patients with a history of Cushing’s syndrome renal failure Participants with less than 80% are going to be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver enzymes (ALT, AST). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Using Microgram/ml - laboratory kit.;Lipid profile (TG, HDL, Total cholestrol). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit.;Liver steatosis index. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Sonography.;Fasting blood sugar. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit.;Total antioxidant capacity. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: laboratory kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Waist to hip ratio. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Non-stretchable tape without any pressure.;Body Mass Index (BMI). Timepoint: The first day of the study and the last day of 8th week. Method of measurement: Weight (kilograms) divided by the square of height (meters).;Sistolic and diastolic blood pressure. Timepoint: The first day of the study and the last day of 8th week. Method of measurement: By mercury sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Izadi
Esfahan University of Medical Sciences
Outcome results
None listed