Male infertility. Oligospermia NOS
Conditions
Interventions
Intervention 1: Interventiion group: 400 IU Vit E will be given orally to 60 infertile men for two months before IVF. Intervention 2: Control group: similar shape placebo will be given orally to 60
Treatment - Drugs
Placebo
Interventiion group: 400 IU Vit E will be given orally to 60 infertile men for two months before IVF.
Control group: similar shape placebo will be given orally to 60 infertile men two months before IVF.
Sponsors
Shiraz University of Medical Sciences- Vice Chancellor for research
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion conditions: 120 of the patients who have been candidated for IVF due to male infertility, have been diagnosed through the semen analysis upon WHO’s criteria and have satisfied the conditions of performing IVF based on existing criteria ( i.e. after semen processing, it contains less than 1-2 million motile sperms, or less than 10 million motile sperms in addition to more than 2 years infertility without any response to IUI ) will be studied. Exclusion conditions: If people are not willing to cooperate in the project or consuming vitamin E, for any reason and also show any sensitivity to vitamin E, will be excluded from the project.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of sperm counts. Timepoint: After two mounts of treatment. Method of measurement: Semen analysis.;Comparison of sperm motility. Timepoint: After two mounts of treatment. Method of measurement: Semen analysis.;Comparison of the percentage of normal shape sperm. Timepoint: After two mounts of treatment. Method of measurement: Semen analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of clinical pregnancy rate. Timepoint: 6-8 weeks after IVF. Method of measurement: By follow up of the patients and sonography.;Comparison of chemical pregnancy rate. Timepoint: 16-18 days after IVF. Method of measurement: By measurement of B-HCG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNiloofar Borzou
Shiraz University Of Medical Scienses
Outcome results
None listed