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Comparison the effect of intravenous ondansetron before or the end of surgery on severity of postoperative nausea and vomiting after diagnostic gynecologic laparoscopy

Comparison of Pre-emptive with Preventive Effect of Intravenous Ondansetron on severity of Postoperative Nausea and Vomiting after Diagnostic Gynecologic Laparoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201402037013N9
Enrollment
80
Registered
2014-02-18
Start date
2013-12-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of medical and surgical care. Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention 1: Iin the control group (n=40), Ondansetron 4mg is administered prior to induction of anesthesia. Intervention 2: In the study group (n=40) Ondansetron 4mg is administered at the end of
Prevention
Iin the control group (n=40), Ondansetron 4mg is administered prior to induction of anesthesia.
In the study group (n=40) Ondansetron 4mg is administered at the end of surgery.

Sponsors

Research Vice Chancellor of Tabriz University, Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women aged 20-40 years; ASA class 1; scheduled for diagnostic gynecologic laparoscopy Exclusion criteria: vaginal hemorrhage; taking any medication, including corticosteroids , opioids and antiemetics; history of systemic disease( cardiovascular, respiratory, renal ,…); history of motion sickness; history of gastrointestinal disease; pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of nausea and vomiting. Timepoint: Recavery and at 3, 6,and 24h postoperatively. Method of measurement: Visual analogue scoring 0-10cm(0=non to 10= vomiting more than 2 times).

Secondary

MeasureTime frame
Total dose of antiemeticafter operation. Timepoint: Recovery and during 24h postoperatively. Method of measurement: mg.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Simin Atashkhoyi

Tabriz University of Medical Sciences

satashkhoyi@gmail.comsiminatashkhoii@yahoo.com+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026