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Prevention of orthodontic pain

A comparison between efficacy of ketoprofen and benzocaine patches on post orthodontic pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014020316466N1
Enrollment
24
Registered
2014-04-17
Start date
2014-02-24
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic pain. Factors influencing health status and contact with health services

Interventions

Intervention 1: benzocaine patch, each 6 hours 1 patch until 3 days The patches contained: Benzocaine(C9H11NO2) ,propylen glycol,di chloro methan,aspartam,poly vynil prolidine,ethanol and hydroxy p
with reducing the speed of dissolving, the contents of the films would not migrate and the final homogenity of the film will be maintained.Hydroxy propyl methyl cellulose and polyvinyl prolidin will
Treatment - Drugs
benzocaine patch, each 6 hours 1 patch until 3 days The patches contained: Benzocaine(C9H11NO2) ,propylen glycol,di chloro methan,aspartam,poly vynil prolidine,ethanol and hydroxy proppyl methyl c
ketoprpfen patch , each 6 hours 1 patch until 3 days The patches contained: Ketoprufen(C16H14O3), propylen glycol,di chloro methan,aspartam,poly vynil prolidine,ethanol and hydroxy proppyl methyl cel

Sponsors

Dentofacial Deformities Research Center of Shahid Beheshti University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: participants, in good general health without any reported systematic diseases; no concurrent use of analgesics and anti-inflammatory drugs; requiring banding of posterior teeth and placement of two or more elastomeric separators as a part of orthodontic treatment; caries-free dentition with healthy periodontium and without any endodontic problems in the posterior part of the mouth; presence of antagonist teeth in the opposite arch and absence of posterior open bite and interdental spaces. Patients were excluded from the study if they used analgesics and anti-inflammatory drugs during the study, did not complete the questionnaire, did not use or improperly used benzocaine or ketoprofen patches,or removed elastomeric separators.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 2 h, 6h, 24h, day2(6 pm), day3(10am and 6 pm) and day7(10 am and 6 pm). Method of measurement: 100 scores visual analogue scale.

Secondary

MeasureTime frame
Production. Timepoint: 2 h, 6h, 24h, day2(6 pm), day3(10am and 6 pm) and day7(10 am and 6 pm). Method of measurement: visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamide Motaharifard- Dr. Naseh

Shahid Beheshti Universiy of Medical Sciences-Private office

motaharifar.h@gmail.com+98 21 2240 3070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026