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L-carnitine effect in diabetic fatty liver disease

L-carnitine effect in the treatment of non alcoholic fatty liver disease in typ 2 diabetic patients and comparision with placebo

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014020316348N2
Enrollment
30
Registered
2014-03-10
Start date
2014-01-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non alcoholic fatty liver disease. Other specified inflammatory liver diseases

Interventions

Intervention 1: IN intervention group: 750 mg L- carnitine, three times a day for three months. Intervention 2: IN control group: plasebo three times a day for three months.
Treatment - Drugs
Placebo
IN intervention group: 750 mg L- carnitine, three times a day for three months
IN control group: plasebo three times a day for three months

Sponsors

Gastroentrology Recerch Center, Ahwaz Jundishapur Medical School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Known case of diabetic type2 ? serum level of alanin aminotranspherase and aspartat aminotranspherase more than 2time of normal? and high level of triglicirid and cholestrol level ? ultrasonograghy evidences of fatty live. Exclusion criteria: any causes of increasing liver enzymes such as viral infections? hemochromatosis ?alfa 1 anti tripsin dificiency?Wilson’s disease? autoimmune diseases? drinking (20 and 10 grams per day for men and women, respectively)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Liver aminotransferase. Timepoint: Before intervention and three months after initiation of the intervention. Method of measurement: Eliza.

Secondary

MeasureTime frame
Serum level of triglicirid and cholestril. Timepoint: Before intervention and three months after initiation of the intervention. Method of measurement: Eliza.;Fasting blood glucos test. Timepoint: Before intervention and three months after initiation of the intervention. Method of measurement: Eliza.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactChobineh Mahmod

Jundishapur University of Medical Sciences

chobineh.m@ajums.ac.ir chobinehmahmod@gmail.com+98 61 1375 7274

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 2, 2026