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prevention of orthodontic pain

The comparison of the effect of 5% naproxen patch and the placebo patch on reduction of fixed orthodontic pain after elastic separator placement

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140203016466N5
Enrollment
30
Registered
2018-01-21
Start date
2017-10-02
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after orthodontic treatment.

Interventions

Intervention 1: placebo patch, every 8 hours up to 3 days. Intervention 2: Naproxen patch, 5%, every 8 hours up to 3 days.
Placebo
Prevention
placebo patch, every 8 hours up to 3 days
Naproxen patch, 5%, every 8 hours up to 3 days

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor
Shahid Beheshti University of Medical Science, School of Dentistry, Orthodontic department
Collaborator

Eligibility

Sex/Gender
All
Age
14 Years to 20 Years

Inclusion criteria

Inclusion criteria: Male and female with 14-20 year old of ages. patients have no pain in teeth and gingiva at the beginning of study. presence of tight contact between first molar with adjacent teeth. the first molars should have antagonist teeth in the opposite jaw. Patients are without posterior open bite. patients present pain after separator placement.

Exclusion criteria

Exclusion criteria: using naproxen is contraindicated in patients.

Design outcomes

Primary

MeasureTime frame
Degree of Primary Pain after orthodontic separator placement. Timepoint: 2hours , 6 hours and 24 hours, 10A.M and 6 P.M on days 2,3 and 7 after separator placement. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazila Akbarianrad

Shahid Beheshti University of Medical Science

rad.nazi@ymail.com+98 21 8870 6783

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026