Asthma. Asthma
Conditions
Interventions
Intervention 1: Routine treatment of asthma plus oral vitamin D 50000 IU single dose, every week, for eight weeks. Intervention 2: Routine treatment of asthma.
Treatment - Drugs
Placebo
Routine treatment of asthma plus oral vitamin D 50000 IU single dose, every week, for eight weeks
Routine treatment of asthma
Sponsors
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: (a) having moderate to severe asthma; (b) age of 18 or above; (c) documented vitamin D deficiency (vitamin D level less than 20 ngr/ml). Exclusion criteria: (a) being pregnant; (b) using calcium or vitamin D during the last 3 months; (c) having history of malabsorption or using drugs effecting vitamin D absorption and metabolism; (d) having other chronic obstructive lung diseases or thoracic skeletal defect.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring forced expiratory volume in the first second (FEV1). Timepoint: at baseline and eight weeks after treatment. Method of measurement: using spirometer.;Measuring forced vital capacity (FVC). Timepoint: at baseline and eight weeks after treatment. Method of measurement: using spirometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting. Timepoint: 8 weeks after treatment. Method of measurement: Question. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mayam Vasheghani
Shahid Beheshti Hospital
Outcome results
None listed