Effect of green tea leaves on lipid profiles and kidney function

A randomized controlled trial of comparison effectiveness of two amounts of green tea leaves with control group on lipid profiles, 24-hour urine protein, blood urea and creatinine in type 2 diabetic patients with nephropathy.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014020114538N2

Enrollment

Registered

2015-11-07

Start date

2015-03-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes melituse. Non-insulin-dependent diabetes mellitus

Interventions

Intervention 1: The first intervention group: this group will consume of green tea (2 gr of green tea leaves infused for 6 min in 200 ml hot water) two times a day before meals (lunch and dinner) for

The first intervention group: this group will consume of green tea (2 gr of green tea leaves infused for 6 min in 200 ml hot water) two times a day before meals (lunch and dinner) for 4 weeks. The gre

The second intervention group: this group will consume 2.5 gr of green tea leaves (brewed in 250 ml of hot water) three times a day before meals (breakfast, lunch and dinner) for 12 weeks.

Control group: this group will not receive any intervention.

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: type 2 diabetic patients with nephropathy? age ranged from 30 to 70 years? not having a history of cancer, hepatic and heart disease. Exclusion criteria: drinking more than two cups of black tea per day? hypertensive patients (>150/90 mm Hg)? patients with GFR less than 20? following a specific diet? changing the dose of medicines within the last 3 months or during the intervention? changing physical activity during the intervention.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
24-hour urine protein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Urinary biochemistry test.;Creatinine. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Urea. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Total cholesterol. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Triglyceride. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Low density lipoprotein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Friedewald's formula.;High density lipoprotein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.	—

Measure

Time frame

24-hour urine protein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Urinary biochemistry test.;Creatinine. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Urea. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Total cholesterol. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Triglyceride. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.;Low density lipoprotein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Friedewald's formula.;High density lipoprotein. Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.

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Secondary

Measure	Time frame
Glycated hemoglobin (HbA1c). Timepoint: At the start of intervention and 12 weeks after the intervention. Method of measurement: Blood biochemical tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Yazdanpanah

Yazd Shahid Sadoughi University of Medical Sciences

yazd456@yahoo.com+98 35 3624 0696

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026