Ketamine-propofol versus alfentanil-propofol for analgesia during cystoscopy

Comparison of the effect of ketamine-propofol versus alfentanil-propofol for analgesia and sedation during cystoscopy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201401313289N7

Enrollment

140

Registered

2014-02-22

Start date

2013-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Pain localized to other parts of lower abdomen

Interventions

Intervention 1: Interventions 1. Alfentanil, 1 µg/kg, intravenous, chemical composition N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylprop

Prevention

Interventions 1. Alfentanil, 1 µg/kg, intravenous, chemical composition N-{1-[2-(4-ethyl-5-oxo-4,5-dihydro-1H-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl}-N-phenylpropanamide, trade m

Interventions 2. Ketamine, 0.5 mg/kg, intravenous, chemical composition RS)-?-(?-Chlorophenyl)-?-(methylamino)cyclohexanone, made in Rotex Medica, Germany.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Elective rigid cystoscopy; either diagnostic or therapeutic; age between 18 and 65. Exclusion Criteria: Patients with allergy to ketamine, propofol, and alfenatnil; pregnancy; emergency cystoscopy; patients on psychiatric medications; alcoholics.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: at time zero and then every 5 minutes. Method of measurement: Cardiac monitoring.;Systolic blood pressure. Timepoint: at time zero and then every 5 minutes. Method of measurement: Mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: at time zero and then every 5 minutes. Method of measurement: Mercury sphygmomanometer.;Arterial O2 saturation. Timepoint: at time zero and then every 5 minutes. Method of measurement: Pulse oximeter.;Respiratory rate. Timepoint: at time zero and then every 5 minutes. Method of measurement: Cardiac monitoring.;Analgesia score. Timepoint: Two hours after cystoscopy. Method of measurement: Visual analog scale.;Sedation score. Timepoint: Two hours after cystoscopy. Method of measurement: Ramsay sedation score.	—

Measure

Time frame

Heart rate. Timepoint: at time zero and then every 5 minutes. Method of measurement: Cardiac monitoring.;Systolic blood pressure. Timepoint: at time zero and then every 5 minutes. Method of measurement: Mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: at time zero and then every 5 minutes. Method of measurement: Mercury sphygmomanometer.;Arterial O2 saturation. Timepoint: at time zero and then every 5 minutes. Method of measurement: Pulse oximeter.;Respiratory rate. Timepoint: at time zero and then every 5 minutes. Method of measurement: Cardiac monitoring.;Analgesia score. Timepoint: Two hours after cystoscopy. Method of measurement: Visual analog scale.;Sedation score. Timepoint: Two hours after cystoscopy. Method of measurement: Ramsay sedation score.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeil Moshiri

Arak University of Medical Sciences

dr_moshiri@arakmu.ac.ir+98 86 3417 3505

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026