Evaluation of effects of adding Dexmedetomidine, Dexamethasone and Na Bicarbonate to Ropivacaine in ultrasound-guided supraclavicular block

Comparative evaluation of effects of adding Dexmedetomidine, Dexamethasone and Na Bicarbonate to Ropivacaine in ultrasound-guided supraclavicular block on the quality of the block in orthopedic surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140129016415N9

Enrollment

120

Registered

2022-06-26

Start date

2022-06-05

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper limb surgery.

Interventions

Intervention 1: First intervention group: 30 micrograms of dexmedetomidine in 1 ml of normal saline is added to the 30 ml of ropivacaine used to block. Intervention 2: Second intervention group: 0.6 m

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and older Weight (Lean body mass) between 50 to 90 kg ASA 1 and 2 Introduced for upper limb surgery (distal to the lower third of arm)

Exclusion criteria

Exclusion criteria: Local infection at the site of the block Existence of coagulation disorder or taking anticoagulants Hypersensitivity to dexmedetomidine, dexamethasone and ropivacaine

Design outcomes

Primary

Measure	Time frame
The interval between the injection of the drug and the onset of anesthesia and immobility. Timepoint: Every 3 minutes. Method of measurement: Evaluation of the movement block is done using 2 movement examinations: 1- Asking the patient to place the index and middle fingers against each other while the other fingers are in the extension position 2- Maintaining the forearm position in a 90 degree position with the arm in a position The performer places the patient's arm perpendicular to the patient's body. The sensory block is evaluated by pressing the Blunted needle on the three points of the dorsal hand, forearm and arm.	—

Measure

Time frame

The interval between the injection of the drug and the onset of anesthesia and immobility. Timepoint: Every 3 minutes. Method of measurement: Evaluation of the movement block is done using 2 movement examinations: 1- Asking the patient to place the index and middle fingers against each other while the other fingers are in the extension position 2- Maintaining the forearm position in a 90 degree position with the arm in a position The performer places the patient's arm perpendicular to the patient's body. The sensory block is evaluated by pressing the Blunted needle on the three points of the dorsal hand, forearm and arm.

—

Secondary

Measure	Time frame
Duration of sensory and motor block. Timepoint: Every 15 minutes. Method of measurement: Evaluation of the movement block is done using 2 movement examinations: 1- Asking the patient to place the index and middle fingers against each other while the other fingers are in the extension position 2- Maintaining the forearm position in a 90 degree position with the arm in a position The performer places the patient's arm perpendicular to the patient's body. The sensory block is evaluated by pressing the Blunted needle on the three points of the dorsal hand, forearm and arm.	—

Measure

Time frame

Duration of sensory and motor block. Timepoint: Every 15 minutes. Method of measurement: Evaluation of the movement block is done using 2 movement examinations: 1- Asking the patient to place the index and middle fingers against each other while the other fingers are in the extension position 2- Maintaining the forearm position in a 90 degree position with the arm in a position The performer places the patient's arm perpendicular to the patient's body. The sensory block is evaluated by pressing the Blunted needle on the three points of the dorsal hand, forearm and arm.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Golparvar

Esfahan University of Medical Sciences

golparvar@med.mui.ac.ir+98 31 3220 1750

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026