Hypotension after spinal anesthesia. Hypotension due to drugs
Conditions
Interventions
Intervention 1: In the study group(n=45) ephedrine 10mg plus phenylephrine 125 ug into 15 ml normal saline at rate of 60 ml/h (within 15 min) is infused. Intervention 2: In the placebo group(n=45)
Prevention
Treatment - Drugs
In the study group(n=45) ephedrine 10mg plus phenylephrine 125 ug into 15 ml normal saline at rate of 60 ml/h (within 15 min) is infused.
In the placebo group(n=45) 15 ml normal saline at rate of 60 ml/h (within 15 min) is infused.
Sponsors
Vice Chancellor for Research, Tabriz University of Medical? Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: term pregnancy; aged 18-40 years; ASA class I or II; scheduled for Cesarean section; scheduled for spinal anesthesia. Exclusion criteria: contraindication for spinal anesthesia; allergy to local anesthetics; Organic dysfunction (cardiovascular; cardiovascular disease,...) fetal abnormalities; maternal hypertension; chronic medication abuse
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Baseline and every 2 minutes after start of study solusion infusion. Method of measurement: mmHg. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of vasoconstrictors. Timepoint: After spinal anesthesia to end of operation. Method of measurement: Doses of medicatins by mg or ug. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Simin Atashkhoyi
Tabriz University of Medical Sciences
Outcome results
None listed