Pain after surgery. Pain, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Bupivacaine 0.25% maximum dose of 2 mg per kilogram of patient weight. Intervention 2: Control group: Morphine 0.1 mg per kg of body weight.
Prevention
Intervention group: Bupivacaine 0.25% maximum dose of 2 mg per kilogram of patient weight
Control group: Morphine 0.1 mg per kg of body weight
Sponsors
Vice Chancellor for Research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 149 Years
Inclusion criteria
Inclusion criteria: Major Inclusion criteria: More than 18 years of age; Undergoing elective supratentorial craniotomy surgery under general anaesthesia due to tumors or vascular lesions. Major exclusion criteria: Coronary artery disease with a contraindication to epinephrine administration; Pain due to intracranial pathology, not differentiated from post-operative pain; Addiction to alcohol and drugs; Active psychiatric illness; Chronic pain after more than 2 weeks drug use; Positive history of migraine headaches; Patient’s inability to understand or answer numeric response questions; Confirmed or potential sensitivity to topical anaesthesia; probable need for post-operative mechanical ventilation; Previous craniotomy or history of radiotherapy of the head; Pregnancy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's pain after surgery. Timepoint: 2, 4, 6, 8, 12 and 24 hours after surgery. Method of measurement: Pain Scale Visual. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFariba Houshmandi
Ghaem Hospital
Outcome results
None listed