Effect of intramuscular administration of Dexamethasone on the induction of labor and duration of labor and its complications

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201401221760N29

Enrollment

120

Registered

2014-03-13

Start date

2014-03-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: induction of labor. Condition 2: duration of labor. Preterm labour and delivery Preterm labour and delivery

Interventions

Intervention 1: Intervention groups: dexamethasone sodium phosphate (2cc) (from Caspian) is injected. After 6 h induction begins.If you do not enter an active phase (3 contractions in 10 minutes with

Treatment - Drugs

Intervention groups: dexamethasone sodium phosphate (2cc) (from Caspian) is injected. After 6 h induction begins.If you do not enter an active phase (3 contractions in 10 minutes with regular dilata

Control group: Sterile water injections (2cc)

Eligibility

Sex/Gender

Female

Age

16 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women with a gestational age of 38 weeks or more; Bishop score greater than or equal to 7; Singleton pregnancy, cephalic; Normal embryo sac. Exclusion criteria: Abnormal vaginal bleeding (risk of placenta previa or placental abruption); History of any systemic diseases (HTN, DM, etc); Receiving any medical treatment except for routine supplementation in pregnancy; Suspected macrosomia (ultrasound or clinical assessment by a skilled person); Excessive uterine distension (polyhydroamnious evidence); presentation non-cephalic; Active phase of labor (cervical dilatation 2-3 cm4-3 with a strong contraction in width, 10); PROM; IUGR10; Fetal distress, bad hips; Any uterine abnormalities or any uterine surgery, including Cesarean delivery on admission;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Reducing the time between the onset of the active phase of labor induction. Timepoint: 6 hours after injection of dexamethasone and induction. Method of measurement: Clinical.;Reduce the duration of the active phase of labor. Timepoint: 38 weeks to 42 weeks of gestation. Method of measurement: Clinical.;Reduction stage II of labor. Timepoint: Dilatation and expulsion of fetus. Method of measurement: Clinical.	—

Measure

Time frame

Reducing the time between the onset of the active phase of labor induction. Timepoint: 6 hours after injection of dexamethasone and induction. Method of measurement: Clinical.;Reduce the duration of the active phase of labor. Timepoint: 38 weeks to 42 weeks of gestation. Method of measurement: Clinical.;Reduction stage II of labor. Timepoint: Dilatation and expulsion of fetus. Method of measurement: Clinical.

—

Secondary

Measure	Time frame
Apgar scores after birth. Timepoint: In the first minutes after birth. Method of measurement: Clinical.;Baby Weight. Timepoint: Birth. Method of measurement: Kg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zeinab Pahlavan

Fatemehzahra Fertility & reproductive Health Research Center

a.uosefnezhad@gmail.com+98 11 1227 4881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026