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The efficacy of 100 and 300 mg gabapentin in the treatment of carpal tunnel syndrome

The efficacy of 100 and 300 mg gabapentin in the treatment of carpal tunnel syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201401144641N7
Enrollment
90
Registered
2014-01-18
Start date
2012-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome. Carpal tunnel syndrome

Interventions

Intervention 1: In the first intervention group, patients will be treated with gabapentin, 100 mg, once a day. Intervention 2: In the second intervention group, patients will be treated with gabapenti
Treatment - Drugs
In the first intervention group, patients will be treated with gabapentin, 100 mg, once a day.
In the second intervention group, patients will be treated with gabapentin, 300 mg, once a day.
In the third group, patients will be given no drugs.

Sponsors

Physical medicine and rehabilitation researches center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with isolated carpal tunnel syndrome; Exclusion criteria: Patients with carpal tunnel syndrome in the setting of other neurological diseases; Patients who had thenar atrophy or were treated with steroid injection in last 3 months; With known contraindication to or prior use of any antiepileptic drugs; Creatinine clearance <30 mL/min; Elevated liver enzymes; Clinically significant hematologic, cardiovascular, renal, or hepatic disease; History of narcotic or alcohol abuse; Previous carpal tunnel syndrome surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of clinical symptoms. Timepoint: Before starting the study and two months after the initiation of the study. Method of measurement: By using Boston carpal tunnel questionnaire.;Functional status. Timepoint: Before starting the study and two months after the initiation of the study. Method of measurement: By using Boston carpal tunnel questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Arash Babaie

Tabriz University of Medical Sciences

arashbabaie@gmail.com+98 41 1337 3967

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026