Effect of Promethazine,Diclofenac and Morphine on pain appendectomy

Promethazine efficacy of Morphine and Diclofenac inter appointment pain reduction in patients between 15-49 years after appendectomy surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014011416221N1

Enrollment

112

Registered

2014-02-15

Start date

2012-04-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: appendectomy. Condition 2: appendectomy. Condition 3: appendectomy. Condition 4: appendectomy. Acute appendicitis Other appendicitis Unspecified appendicitis Other diseases of appendix

Interventions

Intervention 1: Intervention group: Promethazine 50 mg intramuscularly, IM, once postoperative Diclofenac 75 mg intramuscularly, IM, once postoperative. Intervention 2: Control group: Morphine, inject

Treatment - Drugs

Intervention group: Promethazine 50 mg intramuscularly, IM, once postoperative Diclofenac 75 mg intramuscularly, IM, once postoperative

Control group: Morphine, injections of 10 mg intramuscularly, once postoperative

Eligibility

Sex/Gender

All

Age

15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with acute appendicitis between 49-15 years; patient consent Exclusion criteria: drug addiction and smoking; previous surgery; hypotension, underlying disease; complicated appendicitis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain of post operation. Timepoint: half and one oclock post of intervention. Method of measurement: visual analouge scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Tajabadi

Sabzevar University of Medical Sciences

Tajabadia@Medsab.ac.ir+98 57 1444 6070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026