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Effect of L - carnitine on oxidative stress markers in patients with Hyperlipidemia

Effect of L - carnitine on selected parameters of oxidative stress in patients with Hyperlipidemia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014011416214N1
Enrollment
60
Registered
2014-03-09
Start date
2014-02-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidaemia. Hyperlipidaemia, unspecified

Interventions

Intervention 1: In the intervention group, patients with Hyperlipidemia will receive 2 tablet of L - Carnitine (each tablet 1g) for eight weeks. Intervention 2: In the control group, patients with Hyp
Treatment - Drugs
In the intervention group, patients with Hyperlipidemia will receive 2 tablet of L - Carnitine (each tablet 1g) for eight weeks.
In the control group, patients with Hyperlipidemia will receive 2 tablet of placebo (each tablet 1g) for eight weeks.

Sponsors

Vice chancellor for research, Baqiyatallah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Incidence of Hyperlipidemia with Cholesterol levels = 200 mg /dL or Triglycerides levels = 200 mg /dL) or LDL = 130; Age range between 18 and 65 years; Both groups of males and females; Patients do not use Hypolipidemia drugs in 2 month ago. Exclusion criteria: Hypothyroidism disease; Acute Coronary Disease; Renal disease; Pregnancy; Usage of drugs and alcohol; Inflammatory disease; Chronic Liver Disease (Cirrhosis, Hepatitis, etc.); Anti-seizure drugs; Consumption of antioxidant supplements.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Total Antioxidant Capacity. Timepoint: Before and after Intervention. Method of measurement: ELISA.;Serum Malondialdehyde. Timepoint: Before and after Intervention. Method of measurement: Colorimetric.;GSH. Timepoint: Before and after Intervention. Method of measurement: Colorimetric.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHesam Kazemzad

Baqiyatallah University of Medical Science

h.kazemzad@yahoo.com+98 21 8804 0153

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026