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Comparing the effect of three-doses of dexamethasone with a single-dose in reducing intraoperative bleeding, blood pressure, operation time, edema and ecchymosis induced by rhinoplasty

A clinical trial comparing the effect of three-doses of dexamethasone with a single-dose on intraoperative bleeding, blood pressure, operation time, edema and ecchymosis in patients who performed rhinoplasty.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014011316195N1
Enrollment
100
Registered
2014-05-11
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plastic Surgery. Procedures for purposes other than remedying health state

Interventions

Intervention 1: Case group receive three doses of dexamethasone (8mg/kg), the first dose prior to surgery
Second dose inject 8 hours after surgery and the third dose carry 8 hours after the second injection. Intervention 2: In the case group before surgery, a single-dose of dexamethasone (8mg/kg) will be
Treatment - Drugs
Case group receive three doses of dexamethasone (8mg/kg), the first dose prior to surgery
Second dose inject 8 hours after surgery and the third dose carry 8 hours after the second injection.
In the case group before surgery, a single-dose of dexamethasone (8mg/kg) will be injected.

Sponsors

Deputy of Research and Technology of Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients are in the age range of 18 to 30 years; they do not have any history of diseases such as hypertension; heart diseases, diabetes; smoking or drinking alcohol. Exclusion criteria: Patients are not in the age range of 18 to 30 years; or have any history of diseases such as hypertension, heart diseases, diabetes; smoking or drinking alcohol.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Degree of eyelid edema. Timepoint: On the second day after surgery. Method of measurement: Clinical.;Ecchymosis of the soft tissue around the eyes. Timepoint: On the second day after surgery. Method of measurement: Clinical.;Operation time. Timepoint: During the operation. Method of measurement: Clinical.;Bleeding amount. Timepoint: During the operation. Method of measurement: Clinical.;Systolic and diastolic blood pressure. Timepoint: During the operation. Method of measurement: Clinical.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Amani

Babol University of Medical Sciences

neda_amani69@yahoo.com bcrdc90@yahoo.com+98 11 1225 6285

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026