treatment of Restless Leg Syndrome associated end stage renal disease

pramipexole vs. placebo for patients with restless leg syndrome associated chronic renal failure undergoing dialysis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014011216183N1

Enrollment

Registered

2014-04-14

Start date

2014-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

restless leg syndrome, chronic renal failure. Other specified extrapyramidal and movement disorders

Interventions

Intervention 1: Intervention group: patients will be given a quarter of tablet pramipexole 0.18 mg daily for 1 month. Intervention 2: Control group: patinets will be given a quarter of tablet placebo

Treatment - Drugs

Placebo

Intervention group: patients will be given a quarter of tablet pramipexole 0.18 mg daily for 1 month

Control group: patinets will be given a quarter of tablet placebo daily for 1 month

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with End Stage Renal Disease (ESRD); older than 18 years; more 12 week undergoing dialysis; patients with Restless Leg Syndrome (RLS) Exclusion criteria: patients with iron and folate deficiency

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intensity of symptoms. Timepoint: before and 1 month after intervention. Method of measurement: Standard questionnaires.;Frequency of symptoms. Timepoint: before and 1 month after intervention. Method of measurement: Standard questionnaires.	—

Secondary

Measure	Time frame
Side effects. Timepoint: One month after of intervention. Method of measurement: Standard questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Rahmatian

Ilam University of Medical Sciences

aryoobarzan.rahmatian@yahoo.com+98 84 1223 8456

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026