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Effect of periodically versus continuously OCP on Endometrioma recurrence

Comparison of the effect of periodically versus continuously oral contraceptives pills consumption on pain and anatomical recurrence in patients with endometrioma after laparoscopic surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140111016161N8
Enrollment
134
Registered
2018-12-15
Start date
2016-10-22
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

?????????? ??????. Endometriosis of ovary

Interventions

Intervention 1: Intervention group: patients take contraceptive pills continuously for one year. Intervention 2: Control group: patients take contraceptive pill in cyclic form for one year.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Development of endometrioma Age range from 18 to 35 years Unwillingness to pregnancy Anti-Müllerian hormone (AMH) higher than 2.5 Laparoscopic excision of endometrioma

Exclusion criteria

Exclusion criteria: Receive other therapies during the last 6 months (except for non-steroidal anti-inflammatory drugs) Contraindication for estrogen and progesterone regular use Unwillingness to change in menstrual cycles Pelvic inflammatory diseases Varicose veins known malformations of the genitourinary system in previous surgeries known urological, orthopedics, gastrointestinal disorders, and psychological disorder.

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 3, 6 and 12 months after treatment starting. Method of measurement: Visual Analogue Scale.;Anatomical recurrence of ovary endometrium. Timepoint: 3, 6 and 12 months after treatment starting. Method of measurement: sonography.

Secondary

MeasureTime frame
Drug Complications (Increased Endometrial Thickness). Timepoint: 3, 6, and 12 months after starting treatment. Method of measurement: Ultrasound.;Drug Complications (Venous thrombosis). Timepoint: 3, 6, and 12 months after starting treatment. Method of measurement: Medical history and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Reihane hoseini

Tehran University of Medical Sciences

rayh_h@yahoo.com+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026