Medroxyprogesterone acetate and dydrogesterone effect in the treatment of uterine bleeding

Comparison of medroxyprogesterone acetate and dydrogesterone effects on treatment of patients with abnormal vaginal bleeding

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140111016161N7

Enrollment

176

Registered

2018-08-03

Start date

2017-03-21

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vaginal bleeding. Other abnormal uterine and vaginal bleeding

Interventions

Intervention 1: First group: treated with oral medroxyprogesterone acetate tablets, 5 mg every 12 hours from 14th day of menstruation for 10 days. Treatment will continue for 3 months. Intervention 2:

Eligibility

Sex/Gender

Female

Age

30 Years to 45 Years

Inclusion criteria

Inclusion criteria: Endometrial thickness greater than 5 mm Simple endometrial hyperplasia

Exclusion criteria

Exclusion criteria: Endocrine disorders Anatomical problems; History of hormone therapy History of coagulopathy Contraindication for progestin therapy

Design outcomes

Primary

Measure	Time frame
Vaginal bleeding. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: Standard check list designed by the research team.;Endometrium thickness. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: sonography.;Side effects of treatments. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: Standard check list designed by the research team.	—

Measure

Time frame

Vaginal bleeding. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: Standard check list designed by the research team.;Endometrium thickness. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: sonography.;Side effects of treatments. Timepoint: At the beginning of the study (before the intervention) and 3 and 6 months after starting the intervention. Method of measurement: Standard check list designed by the research team.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNewsha Mohamad Nejad

Tehran University of Medical Sciences

newsha1367@yahoo.com+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026