Comparison of effectiveness and speed of shivering treatment after general anesthesia with pethidine and doxapram.

Comparison of the effectiveness and speed of shivering treatment after general anesthesia with pethidine and doxapram in patients undergoing orthopedic surgery and urological surgery referred to Firoozgar Hospital in Tehran.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140109016151N9

Enrollment

Registered

2021-03-12

Start date

2020-08-22

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthopedic surgery. Fracture of humerus following insertion of orthopedic implant, joint prosthesis, or bone plate

Interventions

Intervention 1: Intervention group: Patients who have not responded to non-pharmacological treatment of chills after surgery and are injected with pethidine made by Caspian Pharmaceutical Company (50

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with ASA I, II anesthesia level Patients aged 20 to 60 years undergoing orthopedic and urological surgery Surgery less than 4 hours

Exclusion criteria

Exclusion criteria: History of lung disease Drug allergy to pethidine or doxapram

Design outcomes

Primary

Measure	Time frame
Shivering after surgery. Timepoint: After surgery. Method of measurement: observation.	—

Secondary

Measure	Time frame
Hypoxia. Timepoint: After surgery. Method of measurement: Pulse oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Pournajafian

Iran University of Medical Sciences

a-pournajafian@tums.ac.ir+98 21 8894 6762

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026