Effect of Ciprofloxacin versus Amoxicillin and Metronidazole in recovery of chronic periodontitis

Effect of Ciprofloxacin versus Amoxicillin and Metronidazole as an additional helpful therapy after scaling and root planning in enhancement of periodontal disease clinical parameters of chronic periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014010816141N1

Enrollment

Registered

2014-02-14

Start date

2013-12-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: test2: ciprofloxacin 500mg bid. Intervention 2: test1: 500mg amoxicillin, 250 mg methronidazole Tid.

Treatment - Drugs

test1: 500mg amoxicillin, 250 mg methronidazole Tid

test2: ciprofloxacin 500mg bid

Eligibility

Sex/Gender

All

Age

25 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Systemically healthy; At least 12 teeth (without orthodontic appliances, implant, FPD, crown, third molar); Moderate to severe chronic periodontitis (mean CAL>3); At least 4 teeth with PD>4 and positive BOP; Radiographic view of bone loss Exclusion criteria: Systemic antibiotic and NSAIDS usage in last 2 months; SRP or periodontal surgery in last year; smoking

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Probing depth. Timepoint: 1 month after intervention. Method of measurement: periodontal probe.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazli Rabienejad

Dentistry Faculty

nazlirabi@yahoo.com+98 81 1838 1074

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026