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Effect of prenatal administration of folic acid on serum homocysteine and lipoprotein (a) levels in Methylenetetrahydrofolate reductase polymorphisms

Effect of prenatal administration of folic acid on serum homocysteine and lipoprotein (a) levels in Methylenetetrahydrofolate reductase polymorphisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014010715903N2
Enrollment
90
Registered
2014-05-18
Start date
2014-03-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnant Women. Eclampsia

Interventions

After Administration of folic acid for all the Pregnant women at the dose of 5 mg For 36 week, blood sampling from all the pregnant women Participations before Administration and after 36 weeks
Treatment - Drugs
After Administration of folic acid for all the Pregnant women at the dose of 5 mg For 36 week, blood sampling from all the pregnant women Participations before Administration and after 36 weeks

Sponsors

Drug Applied Research Center
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant wemon with the average age of 20-30 years Exclusion criteria: Without history of heart disease; chronic hypertension; diabetes mellitus; renal disease; collagen tissue disease; history of preterm labor; abortion; drug taking calcium and ferrous sulfate; liver disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Homocysteine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: ELISA method using primary and secondary antibodies by ELISA reader.;Lipoprotein (a). Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Nephlometric Method by Autoanalyzer.

Secondary

MeasureTime frame
LDH. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Urea. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Creatinine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Platelet. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Cell counter.;Urinary creatinine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Nadereh Rashtchizadeh

Drug Applied Research Center

rashtchizadeh@roketmail.com+98 914 114 5493

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026