Non alcoholic fatty liver disease. Non alcoholic fatty liver disease
Conditions
Interventions
Intervention 1: Patients in the intervention group receive 20- 30cc lactulose daily for one month. Lactulose syrup (or Laxilose®, 10 g lactulose/15 mL, Alborzdaru) is a synthetic sugar used to treat
Treatment - Drugs
Treatment - Other
Patients in the intervention group receive 20- 30cc lactulose daily for one month. Lactulose syrup (or Laxilose®, 10 g lactulose/15 mL, Alborzdaru) is a synthetic sugar used to treat constipation. In
The intervention 2: Patients in control group receive vitamin E.
Sponsors
Vice chancellor for research, Tabriz university of medical sciences
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Non alcoholic fatty liver disease, age between 30 and 70 years. Exclusion criteria: Diabetic mellitus, viral hepatitis, congenital hepatitis, drug hepatitis, autoimmune hepatitis, alcohol use, blood triglyceride more than 500mg, inflammatory bowel diseases ( Ulcerative colitis or Crohn's disease), chronic diarrhea, antibiotic use, contraindication of lactolus use, use of medications affecting bowel function, and consent to participate in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver size. Timepoint: Baseline and one month after starting the study. Method of measurement: Ultrasound sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal probiotic count. Timepoint: Baseline and one month after starting the study. Method of measurement: Pour plate technique.;Drug complications. Timepoint: One month after starting the study. Method of measurement: Ask the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Ghotaslou
Tabriz university of medical sciences
Outcome results
None listed