The effect of oral clonidine on hemodynamic changes after thyroid surgery. Other complications of anesthesia
Conditions
Interventions
Intervention 1: Intervention group:The patients of this group received 0.2 mg clonidine orally with water . Intervention 2: Control group: this group receive placebo similar to intervention group.
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: All ASA II patients aged 18-60 years who are candidate for total elective thyroidectomy surgery.
Exclusion criteria
Exclusion criteria: Patients with systemic diseases(cardiovascular, pulmonary, liver and kidney,...) Blood loss over 10% Prediction of patients with difficult airways Drug addiction Use medicines Interfering with clonidine drugs such as Ibuprofen, Metalol, losartan, beta-blockers, diazepam and vitamin B12.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic and diastolic blood pressure. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Mercury barometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure(MAP). Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Mercury barometer.;Heart rate. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes. Method of measurement: Counting in each minutes.;Partial pressure of end tidal of carbondioxide. Timepoint: From the beginning of anesthesia and then every 30 minutes. Method of measurement: Using the Copnograph.;Saturation of peripheral oxygen. Timepoint: From the beginning of anesthesia and then every 30 minutes. Method of measurement: Via the Pulse Oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahman Naghipour
Tabriz University of Medical Sciences
Outcome results
None listed