Chronic sinusitis, unspecified. Sinusitis (chronic) NOS
Conditions
Interventions
Intervention 1: Intervention: herbal nasal drop two times daily 3 drop in each nostril plus nasal irrigation for one month. Intervention 2: Control: Fluticasone spray two puff in each nostril Two tim
Treatment - Drugs
Intervention: herbal nasal drop two times daily 3 drop in each nostril plus nasal irrigation for one month
Control: Fluticasone spray two puff in each nostril Two times daily plus nasal irrigation for one month
Sponsors
Deputy of Research,Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with presence of chronic rhinosinusitis symptoms for at least 12 weeks; positive CT result indicating the opacity and swelling of the sinus; Patients 18 to 75 years of both sexes; Treatment with systemic or nasal antibiotics or corticosteroids within 4 weeks before visit; Treatment wit h oral corticosteroids within the 30 days before visit; Treatment with topical corticosteroids within 15 days before visit. Exclusion criteria: nasal and sinus surgery within the last 5 years; Presence of moderate to severe co-morbid asthma and mild asthma having exacerbation within 30 days prior to trial inclusion; Rhinitis medicamentosa (drug induced rhinitis); Known hypersensitivity to the medication or excipients; The signs and symptoms of bacterial sinusitis (fever = 38.5, ocular complications, severe unilateral frontal headache or toothache); Acute seasonal allergy; other diseases which in the opinion of the investigator disqualifies the patient for trial enrolment(such as heart failure, kidney, lung and liver, drug addiction or alcoholism, neurological or psychiatric diseases, cancer, immunodeficiency) in the past 5 years; any side effect during treatment; Pregnancy; Breastfeeding
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: day 7; day 28. Method of measurement: Ask the patient; The patient stated. | — |
Primary
| Measure | Time frame |
|---|---|
| Recovery. Timepoint: before intervention (day 0), and end of intervention (day 28). Method of measurement: SNOT-22 Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShima Vazifehkhah
School of Traditional Medicine, Tehran University Of Medical Sciense
Outcome results
None listed