Comparison of two kinds of topical drugs in treatment of dermatological infections

Comparison of therapeutic effects of topical colloidal silver and topical clotrimasole in dermatophytosis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201401045092N2

Enrollment

Registered

2014-08-29

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Dermatophytosis. Condition 2: ?uperficial staphylococcal-streptococcal skin infections. Dermatophytosis, unspecified Streptococcal infection, unspecified site

Interventions

Intervention 1: In the treatment group, patients will receive topical colloidal silver three times a day for two weeks. Intervention 2: In the control group patients will receive clotrimasole two time

Treatment - Drugs

In the treatment group, patients will receive topical colloidal silver three times a day for two weeks.

In the control group patients will receive clotrimasole two times a day for four weeks.

Eligibility

Sex/Gender

All

Age

4 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: superficial staphylococcal-streptococcal skin infections; age more than 4 years old; not having immune disorder and organ failure; not having history of allergy to silver compounds and clotrimasole; not using topical drugs in last two weeks in the site of lesion. Exclusion criteria: unwillingness to continue participation in the study, occurring a dermatological reaction due to drugs administered; any kind of drug reaction.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Erythema. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Encrustation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Inflammation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Exudation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.	—

Measure

Time frame

Erythema. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Encrustation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Inflammation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.;Exudation. Timepoint: Before starting the study and at the end of study. Method of measurement: Clinical evaluation and grading based on complete treatment, partial treatment and no treatment.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Afsaneh Parvaneh

Tabriz University of Medical Sciences

apmed82@yahoo.com+98 41 1540 6612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026