Intensity of radiation induced oropharyngeal mucositis. Radiation induced mucositis (oropharyngeal)
Conditions
Interventions
Intervention 1: Herbal extract of plant Salvia officinalis are added to a basic gel to make 2% Sage mouthwash. Patients are instructed to use the mouthwash 3 three times daily from onset of radiothera
Prevention
Placebo
Herbal extract of plant Salvia officinalis are added to a basic gel to make 2% Sage mouthwash. Patients are instructed to use the mouthwash 3 three times daily from onset of radiotherapy for 7 week d
A gel which are equalized in taste, odor, shape and color to 2% Sage mouthwash are used as a placebo mouthwash. Patients are instructed to use the mouthwash 3 three times daily from onset of radiother
Sponsors
Vice chancellor for research and Technology, Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Minimum accumulative dose of 40 Gy according to treatment protocol; 2) Complete exposure of oral cavity to radiation field ; 3) Minimum age of 30, maximum 60 Exclusion criteria : 1)Previous history of head and neck radiotherapy ; 2)Intolerance or hypersensitivity to the mouthwash; 3) Preexisting active oral disease; 4) Any systemic diseases interfering with wound healing
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of oral mucositis. Timepoint: Once a week for 7 week. Method of measurement: Oral Mucositis Assessment Scale (OMAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypersesitivity to drug, patient intoerance. Timepoint: Once a week for7 weeks. Method of measurement: History and physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactIman Gouran
Babol University of Medical Sciences
Outcome results
None listed