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pain during Propofol injection

Comparison of pain on propofol injection by propofol diluted with patient blood, propofol mixed with 0.05lidocaine and propofol diluted with normal saline in patients undergoing surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201401013912N6
Enrollment
120
Registered
2015-08-17
Start date
2014-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain of propofol injection. Other and unspecified general anaesthetics

Interventions

Intervention 1: In the first group Propofol will be diluted with patient blood, and then will be injected. Intervention 2: In second group, propofol mixed with 0.05 lidocaine, and then will be injecte
Treatment - Drugs
In the first group Propofol will be diluted with patient blood, and then will be injected.
In second group, propofol mixed with 0.05 lidocaine, and then will be injected.
In third group, propofol diluted with normal saline, and then will be injected.

Sponsors

Shahrekord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients aged 20 to 60 years who are candidate for elective surgery; ASA class one and two. Exclusion criteria: use of Hypnotic, narcotics or analgesic drugs before surgery; addicted to opioids; alcoholism; hypersensitivity to xylocaine, propofol and eggs; patients with chronic pain syndrome; Thrombophlebitis; sedated and not being able to communicate verbally.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood Pressure. Timepoint: Just before, after injection, and after record of pain. Method of measurement: mmhg by sphegmomanometer.;Pulse. Timepoint: Just before, after injection, and after record of pain. Method of measurement: beat per minute/Radial artery.;Pain. Timepoint: Just before, and after injection, and after record of pain. Method of measurement: VRS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKobra Noorian

Shahrekord University of Medical Sciences

Nooriandehkordy@yahoo.com+98 38333335648

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026