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Treatment of hypopigmented scar (ulcer, burning and etc) with laser and latanoprost drop

Comparison of the efficacy of fractional co2 laser alone and in combination with topical latanoprost drop in repigmentation of hypopigmented scars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013123016002N1
Enrollment
28
Registered
2014-03-19
Start date
2013-04-28
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypopigmented scar. Scar NOS

Interventions

Intervention 1: 6 session of fractional co2 laser treatment with one month interval were done(with fluence of 400mj/cm2).In addition to laser therapy, distill water drop was applied twice daily as pla
Treatment - Other
6 session of fractional co2 laser treatment with one month interval were done(with fluence of 400mj/cm2).In addition to laser therapy, distill water drop was applied twice daily as placebo.
6 session of fractional co2 laser treatment with one month interval were done(with fluence of 400mj/cm2).In addition to laser therapy, topical latanoprost drop was applied twice daily.

Sponsors

Vice chancellor for research, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 15 to 50 years, skin phototype 1 to 4, negative history of systemic retinoid therapy(isotretinoin and acitretin) in recent 6 month. Exclusion criteria: history of hypersensitivity reaction to topical latanoprost, pregnancy, lactation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Repigmentation of hypopigmented scar. Timepoint: baseline, monthly for 6 months, 3month after last session of laser treatment. Method of measurement: Physician observation and scoring according to quartile scale (0-25%,25-50%,50-75%,75-100%).

Secondary

MeasureTime frame
Side effect of latanoprost drop include hypersensitivity reaction. Timepoint: monthly. Method of measurement: clinical evaluation.;Side effects of laser include erythema, pain and burning sensation. Timepoint: monthly. Method of measurement: clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Rezaei

Isfahan University of Medical Sciences

reza.rezaei@resident.mui.ac.ir+98 31 1625 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026