Comparison of Efficacy Between Intramuscular Morphine Sulphateand Diclofenac for Analgesia During burn dressing change

Comparison of intramuscular morphine and intramuscular diclofenac for Analgesia during burn dressing change

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013123015993N1

Enrollment

140

Registered

2014-02-12

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Burn of second degree of lower limb, except ankle and foot. Condition 2: Burn of second degree of ankle and foot. Burn of second degree of hip and lower limb, except ankle and foot Burn of second degree of ankle and foot

Interventions

Intervention 1: In this group, the patients take IM morphine 0.1 mg/kg 15 minutes befor dressing exchang, and pain detect during dressing exchange and in hours of 1, 3, 6 and 12 after that.The Nausea

Treatment - Drugs

In this group, the patients take IM morphine 0.1 mg/kg 15 minutes befor dressing exchang, and pain detect during dressing exchange and in hours of 1, 3, 6 and 12 after that.The Nausea and vomiting in

In this group, the patients take IM Diclofenac 1.5 mg/kg 15 minutes befor dressing exchang, and pain detect during dressing exchange and in hours of 1, 3, 6 and 12 after that.The Nausea and vomiting i

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: the burned patients between 15 and 60 years old, with less than 30%, degree 2 burning in lower extrimities. exclusion criteria: addiction to drugs, more than 30% burning, burning more than or less than 2 degree, pregnant patients, chronic use of analgesic, patients with history of GI bleeding, use of thrombolitics, patients with dispepsia, patient with liver diseases, and patients with renal diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain relief at dressing exchang. Timepoint: At dressing exchange and the hours of 1,3,6 and 12 after dressing exchange. Method of measurement: Pain nomination with VAS questionnaires.	—

Secondary

Measure	Time frame
Incidence of nausea and vomiting. Timepoint: Observation within dressing exchane untill 12 hours. Method of measurement: History and Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavid Sabeti

Qazvin University of Medical Sciences

jsabeti@qums.ac.ir+98 28 1333 5800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026