Nasal polyposis. Polyp of nasal cavity
Conditions
Interventions
Intervention 1: Standard treatment (including baclofen nasal spray and loratadine tablet) plus nasal irrigation with 20 ml normal saline solution including 1 gr/l vancomycin, three time a day for eigh
Treatment - Drugs
Placebo
Standard treatment (including baclofen nasal spray and loratadine tablet) plus nasal irrigation with 20 ml normal saline solution including 1 gr/l vancomycin, three time a day for eight weeks
Standard treatment (including baclofen nasal spray and loratadine tablet) plus nasal irrigation with 20 ml normal saline solution, three time a day for eight weeks
Sponsors
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (a) having chronic sinusitis in accordance with polyposis; (b) age of 18 to 70 years. Exclusion criteria: (a) having immune system disorder; (b) having systemic diseases such as diabetes, chronic renal failure, malignancy, cystic fibrosis, or granolomatosis disease; (c) being pregnant.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Polyposis recurrence. Timepoint: in the second, fourth, and sixth months after surgery. Method of measurement: based on nasal endoscopic criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Staph aureus infection in nasal cavity. Timepoint: in the second month after surgery. Method of measurement: using sterile soap from medial meatus and microbial culture.;Drug side effects (including nasal dryness and/or sensitivity). Timepoint: 8 weeks after surgery. Method of measurement: Quesytion from patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Javad Yazdani
Resident of Ear-Nose-Throat
Outcome results
None listed