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efficacy of Fluorometholone versus Loteprednol eye drops after photorefractive keratectomy

Clinical efficacy of Fluorometholone versus Loteprednol eye drops after photorefractive keratectomy: A triple-blinded randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20131229015975N6
Enrollment
100
Registered
2020-02-06
Start date
2016-04-02
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Myopia correction by photorefractive keratectomy. Condition 2: Astigmatism correction by photorefractive keratectomy. Myopia, unspecified eye Unspecified astigmatism

Interventions

Intervention 1: Intervention group: One eye in each subject was randomly allocated to use of 0.1% Fluorometholone eye drops packaged in droppers (Floucort®, SinaDarou Co., Tehran, Iran) that was presc

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Stable refraction error for at least 12 months Myopia between -8.0 to -1.0 diopters Astigmatism less than 4.0 diopters Normal eye examination

Exclusion criteria

Exclusion criteria: Unwillingness to participate or continue administration of another topical medication need to increase the topical steroid dosage treatment-related complications

Design outcomes

Primary

MeasureTime frame
Change in best corrected distance visual acuity (BCDVA). Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Eye examination, slit-lamp biomicroscopy and fundus examination assessment.;Corneal optical density. Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Corneal densitometry was performed with a rotating camera cornea tomography system (Pentacam®).

Secondary

MeasureTime frame
Intraocular pressure. Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Goldman applanation tonometry (GAT).;Side effects. Timepoint: On days one, three, and five and then at months one and three postoperatively. Method of measurement: Clinical assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Pourazizi

Esfahan University of Medical Sciences

m.pourazizi@yahoo.com+98 31 3445 2031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026