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Effect of Q10 supplementation on cardiovascular bio markers in patients undergoing open heart surgery. "

Double blinded clinical trial on the effect of Q10 supplement on the level of CK-MB and Troponine enzymes in patients undergoing Coronary Artery Bypass Graft (CABG) surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013122815957N1
Enrollment
80
Registered
2014-09-22
Start date
2013-12-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic ischaemic heart disease. Chronic ischaemic heart disease, unspecified

Interventions

Intervention 1: Intervention group: 150 mg Q10 supplementation will give to individuals in three divided doses (Q10 in capsule form -Iran Drug maker Exir Pharmaceuticals) for 7 days. Intervention 2: C
Treatment - Drugs
Intervention group: 150 mg Q10 supplementation will give to individuals in three divided doses (Q10 in capsule form -Iran Drug maker Exir Pharmaceuticals) for 7 days
Control group: The control group will receive capsules with the same shape, from the same company with no therapeutic content (just the color) ,three times a day for 7 days

Sponsors

Vice Chancellor for research of Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 80 patients' eligible for CABG surgery; Tehran Heart Hospital Rajai Exclusion criteria: Patients with the following conditions (recent intake of antioxidants either warfarin. (a month) ; Valve replacement; and those with BMI above 30; Kidney disease (cr above 1.5)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Level of Troponin. Timepoint: Pre-intervention and post-intervention and 24-hour, seven days after surgery. Method of measurement: ELISA Kit.

Secondary

MeasureTime frame
Levels of CK-MB. Timepoint: Pre-intervention and post-intervention and 24-hour, seven days after surgery. Method of measurement: ELISA Kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Moludi

Department of Clinical Nutrition, School of Nutrition and Dietitics, Tehran University of Medical Sc

J-MOLUDI@RAZI.TUMS.AC.IR+98 21 8897 4463

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026